GCK Polyclonal Antibody
RD75855A
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGCK
Overview
- SupplierReddot Biotech
- Product NameGCK Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID2645
- Target nameGCK
- Target descriptionglucokinase
- Target synonymsATP:D-hexose 6-phosphotransferase; FGQTL3; GK; GLK; glucokinase (hexokinase 4); hexokinase D, pancreatic isozyme; hexokinase type IV; hexokinase-4; HHF3; HK IV; HK4; HKIV; HXKP; LGLK; MODY2; PNDM1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionHexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203