GCLM Antibody / Glutamate-Cysteine Ligase Regulatory Subunit

Biorbyt

GCLM Antibody / Glutamate-Cysteine Ligase Regulatory Subunit

10

Optimal dilution of the GCLM antibody should be determined by the researcher.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT IHC-P, WB

Research Use Only

Monoclonal

CPTC-GCLM-1

Unconjugated

GCLM

glutamate-cysteine ligase modifier subunit

gamma-ECS regulatory subunit; gamma-glutamylcysteine synthetase regulatory subunit; GCS light chain; GLCLR; glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD); glutamate-cysteine ligase modifier subunit delta2 alternative splicing; glutamate-cysteine ligase regulatory protein; glutamate--cysteine ligase regulatory subunit; GSC light chain

Mouse

IgG2a

Glutamate--cysteine ligase regulatory subunit

GCLM, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.

Human

-20°C,2°C to 8°C

12352203