More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/GCLM antibody

GCLM antibody

Research Use Only
GTX114075
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGCLM
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    GCLM antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.21 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID2730
  • Target name
    GCLM
  • Target description
    glutamate-cysteine ligase modifier subunit
  • Target synonyms
    gamma-ECS regulatory subunit; gamma-glutamylcysteine synthetase regulatory subunit; GCS light chain; GLCLR; glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD); glutamate-cysteine ligase modifier subunit delta2 alternative splicing; glutamate-cysteine ligase regulatory protein; glutamate--cysteine ligase regulatory subunit; GSC light chain
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP48507
  • Protein Name
    Glutamate--cysteine ligase regulatory subunit
  • Scientific Description
    Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Ferroptosis regulation by the NGLY1/NFE2L1 pathway. Forcina GC et al., 2022 Mar 15, Proc Natl Acad Sci U S A
    Read more
  • BACH1, the master regulator of oxidative stress, has a dual effect on CFTR expression. NandyMazumdar M et al., 2021 Oct 29, Biochem J
    Read more
  • Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities. Hori Y et al., 2021 May 3, Cells
    Read more
  • The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated alpha-MSH in keratinocytes via Nrf2-mediated antioxidant pathways. Hseu YC et al., 2021 Aug, Redox Biol
    Read more
  • xCT/SLC7A11 antiporter function inhibits HIV-1 infection. Rabinowitz J et al., 2021 Apr, Virology
    Read more
  • Mechanisms of Fasting-Mediated Protection against Renal Injury and Fibrosis Development after Ischemic Acute Kidney Injury. Rojas-Morales P et al., 2019 Aug 22, Biomolecules
    Read more
  • The Protective Effect of Hispidin against Hydrogen Peroxide-Induced Oxidative Stress in ARPE-19 Cells via Nrf2 Signaling Pathway. Huang SY et al., 2019 Aug 19, Biomolecules
    Read more
  • Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 Signaling. Wu CT et al., 2019, Oxid Med Cell Longev
    Read more
  • Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway. Wu YL et al., 2018 Feb 1, Free Radic Biol Med
    Read more
  • A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Choi EJ et al., 2017 Sep 14, Oncogene
    Read more