GDF-15, Cynomolgus (HEK293, Fc)
HY-P77681
Protein IDG7PWZ3
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameGDF-15, Cynomolgus (HEK293, Fc)
- Delivery Days Customer10
- CertificationResearch Use Only
- Gene ID102117226
- Target nameGDF15
- Target descriptiongrowth differentiation factor 15
- Target synonymsgrowth/differentiation factor 15
- Protein IDG7PWZ3
- Protein NameGrowth/differentiation factor 15
- Scientific DescriptionGrowth differentiation factor 15 (GDF-15) is a polypeptide hormone belonging to the transforming growth factor beta (TGF-beta) superfamily. GDF-15 is also known as non-steroidal anti-inflammatory drug activating Gene-1 (NAG-1), placental transforming growth factor-beta (PTGFB), prostate-derived factor (PDF), and placental bone morphogenetic protein (PLAB). GDF-15 binds to glial cell-derived neurotrophic factor (GDNF) family receptor alpha-like protein (GFRAL) and is involved in aging, cancer, and metabolic processes. GFRAL-GDF15 does not affect SMAD activity and activates intracellular signals including RET, AKT, ERK1/2, and phospholipase C (PLCgamma)[1]. GDF-15 Protein, Cynomolgus (HEK293, Fc) has 112 amino acids expressed by HEK293 cells with N-terminal hFc tag.
- UNSPSC41116100
- SpeciesPrimate