Gefitinib

MedChem Express

Gefitinib [184475-35-2]

10

184475-35-2

Research Use Only

99.95

C22H24ClFN4O3

446.90

Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis , which can be used for cancer related research, such as Lung cancer and breast cancer [1] [2] [5] .

ClC1=C(C=CC(NC2=NC=NC3=C2C=C(C(OC)=C3)OCCCN4CCOCC4)=C1)F

-20°C,2°C to 8°C

12352200