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ProductsBack/Gefitinib [184475-35-2]

Gefitinib [184475-35-2]

M1749

CAS Number184475-35-2

Product group Chemicals

Estimated Purity99.97%

Molecular Weight446.90

Overview

Supplier
AbMole BioScience
Product Name
Gefitinib [184475-35-2]
Delivery Days Customer
7
CAS Number
184475-35-2
Certification
Research Use Only
Estimated Purity
99.97%
Molecular Formula
C22H24ClFN4O3
Molecular Weight
446.90
Scientific Description
Gefitinib (ZD1839) is an EGFR tyrosine kinase and Akt phosphorylation inhibitor. Gefitinib significantly down-regulates CD47 expression and increases DC phagocytosis in non-small cell lung cancer cells such as PC9, H1437 and H1573. Gefitinib combined with CD47 antibody can enhance the phagocytosis of macrophages.
SMILES
COC1=C(OCCCN2CCOCC2)C=C3C(=NC=NC3=C1)NC4=CC=C(F)C(=C4)Cl
Storage Instruction
-20°C
UNSPSC
12161500

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