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Gefitinib impurity 1 [675126-26-8]

Gefitinib impurity 1 [675126-26-8]

T40785
TargetMol Chemicals
CAS Number675126-26-8
Product group Chemicals
Molecular Weight321.33
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Gefitinib impurity 1 [675126-26-8]
  • Delivery Days Customer
    14
  • CAS Number
    675126-26-8
  • Certification
    Research Use Only
  • Chemical Name
    Gefitinib impurity 1
  • Molecular Formula
    C15H19N3O5
  • Molecular Weight
    321.33
  • Scientific Description
    Gefitinib impurity 1 is a compound derived from Gefitinib, a potent and selective EGFR tyrosine kinase inhibitor (IC 50 = 33 nM). This orally active compound selectively inhibits tumor cell growth stimulated by EGF (IC 50 = 54 nM) and inhibits EGFR autophosphorylation induced by EGF in tumor cells. Additionally, Gefitinib induces autophagy and exhibits antitumor activity.
  • Shelf life instruction
    3 years
  • SMILES
    COc1cc(c(cc1OCCCN1CCOCC1)C#N)[N+]([O-])=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200