Geminin antibody
GTX116125
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetGMNN
Overview
- SupplierGeneTex
- Product NameGeminin antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID51053
- Target nameGMNN
- Target descriptiongeminin DNA replication inhibitor
- Target synonymsGem, MGORS6, geminin
- HostRabbit
- IsotypeIgG
- Protein IDO75496
- Protein NameGeminin
- Scientific DescriptionInhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Caller LG, Davies CTR, Antrobus R, et al. Temporal Proteomic Analysis of BK Polyomavirus Infection Reveals Virus-Induced G(2) Arrest and Highly Effective Evasion of Innate Immune Sensing. J Virol. 2019,93(16). doi: 10.1128/JVI.00595-19Read this paper


![IHC-P analysis of human chronic lymphocytic leukemia tissue using GTX01909 Geminin antibody [EM6]. Note intense nuclear staining of proliferating neoplastic cells.](https://www.genetex.com/upload/website/prouct_img/normal/GTX01909/GTX01909_20200811_IHC-P_40_w_23053121_553.webp)




