WB analysis of HEK293 (1) and GFI1(AA: 2-250)-hIgGFc transfected HEK293 (2) cell lysate using GTX82779 GFI1 antibody [5D7].
WB analysis of HEK293 (1) and GFI1(AA: 2-250)-hIgGFc transfected HEK293 (2) cell lysate using GTX82779 GFI1 antibody [5D7].
GFI1 antibody [5D7]
GTX82779
Overview
- SupplierGeneTex
- Product NameGFI1 antibody [5D7]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5D7
- ConjugateUnconjugated
- Gene ID2672
- Target nameGFI1
- Target descriptiongrowth factor independent 1 transcriptional repressor
- Target synonymsGFI-1; GFI1A; growth factor independence-1; growth factor independent 1 transcription repressor; growth factor independent protein 1; SCN2; zinc finger protein 163; zinc finger protein Gfi-1; ZNF163
- HostMouse
- IsotypeIgG1
- Protein IDQ99684
- Protein NameZinc finger protein Gfi-1
- Scientific DescriptionThis gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203