GGCX antibody, C-term

GeneTex

GGCX antibody, C-term

7

This antibody is expected to recognize both isoforms (NP_000812.2; NP_001135741.1).

WB: 0.3-1microg/ml. IHC-P: 5-10microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

GGCX

gamma-glutamyl carboxylase

peptidyl-glutamate 4-carboxylase; vitamin K-dependent gamma-carboxylase; VKCFD1

Goat

IgG

Vitamin K-dependent gamma-carboxylase

This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Human

-20°C or -80°C,2°C to 8°C

12352203