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GGTI298

HY-100876
MedChem Express
CAS Number180977-44-0
Product group Chemicals
Estimated Purity85.0
Molecular Weight479.63
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GGTI298 [180977-44-0]
  • Delivery Days Customer
    10
  • CAS Number
    180977-44-0
  • Certification
    Research Use Only
  • Estimated Purity
    85.0
  • Molecular Formula
    C27H33N3O3S
  • Molecular Weight
    479.63
  • Scientific Description
    GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC 50 values of 3 and > 20 microM in vivo, respectively.
  • SMILES
    CC(C)C[C@@H](C(OC)=O)NC(C1=CC=C(NC[C@@H](N)CS)C=C1C2=C3C=CC=CC3=CC=C2)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200