GGTI298
HY-100876
CAS Number180977-44-0
Product group Chemicals
Estimated Purity85.0
Molecular Weight479.63
Overview
- SupplierMedChem Express
- Product NameGGTI298 [180977-44-0]
- Delivery Days Customer10
- CAS Number180977-44-0
- Estimated Purity85.0
- Molecular FormulaC27H33N3O3S
- Molecular Weight479.63
- Scientific DescriptionGGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC 50 values of 3 and > 20 microM in vivo, respectively.
- SMILESCC(C)C[C@@H](C(OC)=O)NC(C1=CC=C(NC[C@@H](N)CS)C=C1C2=C3C=CC=CC3=CC=C2)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200