Ginsenoside Rd [52705-93-8]

MedChem Express

Ginsenoside Rd [52705-93-8]

5

52705-93-8

Research Use Only

99.88

C48H82O18

947.15

Ginsenoside Rd inhibits TNFalpha-induced NF-kappaB transcriptional activity with an IC50 of 12.05+/-0.82 microM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0+/-4.5 microM, 78.4+/-5.3 microM, 81.7+/-2.6 microM, and 85.1+/-9.1 microM, respectively.

C[C@](CC/C=C(C)/C)([C@]1([H])[C@]([C@H](O)C[C@@]2([H])[C@@]3(C)CC[C@]4([H])[C@]2(C)CC[C@H](O[C@]5([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C4(C)C)([H])[C@@]3(C)CC1)O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O

-20°C,2°C to 8°C

12352200