Ginsenoside-Rd

AbMole BioScience

Ginsenoside-Rd

9

52705-93-8

Chemical

Research Use Only

C48H82O18

947.15

Ginsenoside Rd inhibited NF-kappaB transcriptional activity induced by TNFalfa with IC50 of 12.05±0.82 uM. Ginsenoside Rd inhibited the expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibited CYP2D6, CYP1A2, CYP3A4 and CYP2C9 with IC50 of 58.0±4.5 uM, 78.4±5.3 uM, 81.7±2.6 uM and 85.1±9.1 uM, respectively.

CC(C)=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C2CCC3(C)C2C(O)CC4C5(C)CCC(OC6OC(CO)C(O)C(O)C6OC7OC(CO)C(O)C(O)C7O)C(C)(C)C5CCC34C

12352200