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ProductsBack/Glucagon antibody [EP74]

Glucagon antibody [EP74]

Research Use Only
GTX01699
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetGCG
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Overview

  • Supplier
    GeneTex
  • Product Name
    Glucagon antibody [EP74]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    EP74
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID2641
  • Target name
    GCG
  • Target description
    glucagon
  • Target synonyms
    glicentin-related polypeptide; GLP1; GLP-1; GLP2; glucagon-like peptide 1; glucagon-like peptide 2; GRPP; preproglucagon; pro-glucagon
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP01275
  • Protein Name
    Glucagon
  • Scientific Description
    The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced. Seiron P et al., 2019 Oct, J Pathol Clin Res
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  • Mixed acinar-neuroendocrine carcinoma of the pancreas: a case report and a review. Jakobsen M et al., 2016 Dec, Histol Histopathol
    Read more
  • Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes. Krogvold L et al., 2016 Mar, Diabetologia
    Read more