Western blot analysis of GluR2 phosphorylation expression in Mouse braintissue lysates,The lane on the left is treated with the antigen-specific peptide.
Western blot analysis of GluR2 phosphorylation expression in Mouse braintissue lysates,The lane on the left is treated with the antigen-specific peptide.
GluR2 (phospho Ser880) antibody
GTX52325
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGRIA2
Overview
- SupplierGeneTex
- Product NameGluR2 (phospho Ser880) antibody
- Delivery Days Customer9
- Antibody SpecificityGRIA2
- Application Supplier NoteWB 1:500-1:2000, IHC 1:50-1:200
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2891
- Target nameGRIA2
- Target descriptionglutamate ionotropic receptor AMPA type subunit 2
- Target synonymsAMPA-selective glutamate receptor 2; GluA2; GLUR2; gluR-2; GLURB; gluR-B; GluR-K2; glutamate receptor 2; glutamate receptor, ionotropic, AMPA 2; HBGR2; NEDLIB
- HostRabbit
- IsotypeIgG
- Protein IDP42262
- Protein NameGlutamate receptor 2
- Scientific DescriptionGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203