Glutathione Reductase antibody [N2C2], Internal
GTX114199
ApplicationsElectron Microscopy, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetGSR
Overview
- SupplierGeneTex
- Product NameGlutathione Reductase antibody [N2C2], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsElectron Microscopy, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.21 mg/ml
- ConjugateUnconjugated
- Gene ID2936
- Target nameGSR
- Target descriptionglutathione-disulfide reductase
- Target synonymsCNSHA10, GR, GSRD, HEL-75, HEL-S-122m, glutathione reductase, mitochondrial, GRase, epididymis luminal protein 75, epididymis secretory sperm binding protein Li 122m, glutathione S-reductase
- HostRabbit
- IsotypeIgG
- Protein IDP00390
- Protein NameGlutathione reductase, mitochondrial
- Scientific DescriptionThis gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
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- Pek E, Canbey Göret C, Hacıvelioğlu S, et al. The immunohistochemical and histologic effects of contrast medium on uterus, fallopian tubes and ovaries, given during hysterosalpingography: rat study. J Turk Ger Gynecol Assoc. 2020,21(4):243-254. doi: 10.4274/jtgga.galenos.2020.2019.0067Read this paper
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- Maclean KN, Jiang H, Aivazidis S, et al. Taurine treatment prevents derangement of the hepatic γ-glutamyl cycle and methylglyoxal metabolism in a mouse model of classical homocystinuria: regulatory crosstalk between thiol and sulfinic acid metabolism. FASEB J. 2018,32(3):1265-1280. doi: 10.1096/fj.201700586RRead this paper
- Zimnol A, Amann K, Mandel P, et al. Angiotensin II type 1a receptor-deficient mice develop angiotensin II-induced oxidative stress and DNA damage without blood pressure increase. Am J Physiol Renal Physiol. 2017,313(6):F1264-F1273. doi: 10.1152/ajprenal.00183.2017Read this paper
- Wang YY, Chen YK, Hsu YL, et al. Synthetic β-nitrostyrene derivative CYT-Rx20 as inhibitor of oral cancer cell proliferation and tumor growth through glutathione suppression and reactive oxygen species induction. Head Neck. 2017,39(6):1055-1064. doi: 10.1002/hed.24664Read this paper
- Huang CS, Lin AH, Yang TC, et al. Shikonin inhibits oxidized LDL-induced monocyte adhesion by suppressing NFκB activation via up-regulation of PI3K/Akt/Nrf2-dependent antioxidation in EA.hy926 endothelial cells. Biochem Pharmacol. 2015,93(3):352-61. doi: 10.1016/j.bcp.2014.12.005Read this paper
- Chou HC, Chan HL. Effect of glutathione reductase knockdown in response to UVB-induced oxidative stress in human lung adenocarcinoma. Proteome Sci. 2014,12(1):2. doi: 10.1186/1477-5956-12-2Read this paper




