IHC-P analysis of human prostate and stomach carcinoma tissue using GTX15747 Glyoxalase I antibody [Glo1a]. Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer for 20 minutes Dilution : 1:800
![WB analysis of 25 ug of various whole cell lysates using GTX15747 Glyoxalase I antibody [Glo1a]. Dilution : 1:1000](https://www.genetex.com/upload/website/prouct_img/normal/GTX15747/GTX15747_1521_WB_w_23060620_986.webp "WB analysis of 25 ug of various whole cell lysates using GTX15747 Glyoxalase I antibody [Glo1a]. Dilution : 1:1000")
![WB analysis of whole cell extracts (30 microg lysate) of MCF7 (Lane 1), HeLa (Lane 2), MDA-MB-231 (Lane 3), HL-60 (Lane 4), MOLT-4 (Lane 5), LNCaP (Lane 6), T-47D (Lane 7), U-87 MG (Lane 8) and A549 (Lane 9) using GTX15747 Glyoxalase I antibody [Glo1a]. Dilution : 1:1000](https://www.genetex.com/upload/website/prouct_img/normal/GTX15747/GTX15747_1522_WB_w_23060620_914.webp "WB analysis of whole cell extracts (30 microg lysate) of MCF7 (Lane 1), HeLa (Lane 2), MDA-MB-231 (Lane 3), HL-60 (Lane 4), MOLT-4 (Lane 5), LNCaP (Lane 6), T-47D (Lane 7), U-87 MG (Lane 8) and A549 (Lane 9) using GTX15747 Glyoxalase I antibody [Glo1a]. Dilution : 1:1000")
IHC-P analysis of human prostate and stomach carcinoma tissue using GTX15747 Glyoxalase I antibody [Glo1a]. Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer for 20 minutes Dilution : 1:800
Glyoxalase I antibody [Glo1a]
GTX15747
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Primate, Rat
TargetGLO1
Overview
- SupplierGeneTex
- Product NameGlyoxalase I antibody [Glo1a]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. ICC/IF: 1:800. IHC-P: 1:800. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGlo1a
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2739
- Target nameGLO1
- Target descriptionglyoxalase I
- Target synonymsaldoketomutase; epididymis secretory protein Li 74; GLOD1; glx I; GLYI; glyoxalase domain containing 1; HEL-S-74; ketone-aldehyde mutase; lactoyl glutathione lyase; lactoylglutathione lyase; methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase
- HostMouse
- IsotypeIgG
- Protein IDQ04760
- Protein NameLactoylglutathione lyase
- Scientific DescriptionThe enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Primate, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Glyoxalase-1-Dependent Methylglyoxal Depletion Sustains PD-L1 Expression in Metastatic Prostate Cancer Cells: A Novel Mechanism in Cancer Immunosurveillance Escape and a Potential Novel Target to Overcome PD-L1 Blockade Resistance. Antognelli C et al., 2021 Jun 13, Cancers (Basel)Read more