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GNB1 antibody

GTX114442
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
TargetGNB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    GNB1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.32 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2782
  • Target name
    GNB1
  • Target description
    G protein subunit beta 1
  • Target synonyms
    HG2A, MDS, MRD42, guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, beta subunit, signal-transducing proteins GS/GI, guanine nucleotide binding protein (G protein), beta polypeptide 1, heterotrimeric guanine nucleotide-binding protein 2A, testicular tissue protein Li 72, transducin beta chain 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP62873
  • Protein Name
    Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  • Scientific Description
    Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Encephalopathy-causing mutations in Gbeta1 (GNB1) alter regulation of neuronal GIRK channels. Reddy HP et al., 2021 Sep 24, iScience
    Read this paper
  • The Gbeta1 and Gbeta3 Subunits Differentially Regulate Rat Vascular Kv7 Channels. Greenwood IA et al., 2019, Front Physiol
    Read this paper
  • Transducin beta-Subunit Can Interact with Multiple G-Protein gamma-Subunits to Enable Light Detection by Rod Photoreceptors. Dexter PM et al., 2018 May-Jun, eNeuro
    Read this paper
  • Identification of up- and down-regulated proteins in doxorubicin-resistant uterine cancer cells: reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance. May EW et al., 2014 Dec, Pharmacol Res
    Read this paper
  • Gbeta1 controls collective cell migration by regulating the protrusive activity of leader cells in the posterior lateral line primordium. Xu H et al., 2014 Jan 15, Dev Biol
    Read this paper