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GNB1 antibody

GTX114442
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetGNB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    GNB1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.32 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2782
  • Target name
    GNB1
  • Target description
    G protein subunit beta 1
  • Target synonyms
    HG2A, MDS, MRD42, guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, beta subunit, signal-transducing proteins GS/GI, guanine nucleotide binding protein (G protein), beta polypeptide 1, heterotrimeric guanine nucleotide-binding protein 2A, testicular tissue protein Li 72, transducin beta chain 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP62873
  • Protein Name
    Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  • Scientific Description
    Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Reddy HP, Yakubovich D, Keren-Raifman T, et al. Encephalopathy-causing mutations in Gβ(1) (GNB1) alter regulation of neuronal GIRK channels. iScience. 2021,24(9):103018. doi: 10.1016/j.isci.2021.103018
    Read this paper
  • Greenwood IA, Stott JB. The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels. Front Physiol. 2019,10:1573. doi: 10.3389/fphys.2019.01573
    Read this paper
  • Dexter PM, Lobanova ES, Finkelstein S, et al. Transducin β-Subunit Can Interact with Multiple G-Protein γ-Subunits to Enable Light Detection by Rod Photoreceptors. eNeuro. 2018,5(3). doi: 10.1523/ENEURO.0144-18.2018
    Read this paper
  • May EW, Lin ST, Lin CC, et al. Identification of up- and down-regulated proteins in doxorubicin-resistant uterine cancer cells: reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance. Pharmacol Res. 2014,90:1-17. doi: 10.1016/j.phrs.2014.08.007
    Read this paper
  • Xu H, Ye D, Behra M, et al. Gβ1 controls collective cell migration by regulating the protrusive activity of leader cells in the posterior lateral line primordium. Dev Biol. 2014,385(2):316-27. doi: 10.1016/j.ydbio.2013.10.027
    Read this paper