GNE-1858
HY-135892
CAS Number2680616-96-8
Product group Chemicals
Estimated Purity99.42
Molecular Weight428.48
Overview
- SupplierMedChem Express
- Product NameGNE-1858 [2680616-96-8]
- Delivery Days Customer9
- CAS Number2680616-96-8
- CertificationResearch Use Only
- Estimated Purity99.42
- Molecular FormulaC21H26F2N8
- Molecular Weight428.48
- Scientific DescriptionGNE-1858 is a potent and ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor, with IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA, respectively[1].
- SMILESFC1(CCN(C2=NC(C3CCNC3)=CC(NC4=CC5=C(C=N4)C=NN5C(C)C)=N2)C1)F
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200