GNE-207 [2158266-58-9]
T15399
Overview
- SupplierTargetMol Chemicals
- Product NameGNE-207 [2158266-58-9]
- Delivery Days Customer86
- CAS Number2158266-58-9
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameGNE-207
- Molecular FormulaC29H30N6O3
- Molecular Weight510.59
- Scientific DescriptionGNE-207 is a selective and orally bioavailable inhibitor of the bromodomain of CBP (IC50: 1 nM). It has a selective index of >2500-fold against BRD4 (1). GNE-207 displays excellent CBP potency (EC50: 18 nM for MYC expression in MV-4-11 cells).
- Shelf life instruction3 years
- SMILESCNC(=O)c1ccc(cn1)-c1cc2cccc(-c3nn(C4CCOCC4)c4CCN(Cc34)C(C)=O)c2cn1
- Storage Instruction-20°C
- UNSPSC12352200