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GNE-490 [1033739-92-2]

GNE-490 [1033739-92-2]

T22339
TargetMol Chemicals
CAS Number1033739-92-2
DownloadMSDS
Product group Chemicals
Molecular Weight386.47
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GNE-490 [1033739-92-2]
  • Delivery Days Customer
    9
  • CAS Number
    1033739-92-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    GNE-490
  • Molecular Formula
    C18H22N6O2S
  • Molecular Weight
    386.47
  • Scientific Description
    GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta and PI3Kgamma, respectively. GNE-490 has >200 fold selectivity for mTOR (IC50 = 750 nM).
  • Shelf life instruction
    3 years
  • SMILES
    Cc1nc(N)ncc1-c1nc(N2CCOCC2)c2sc(cc2n1)C(C)(C)O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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Chemical Structure
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