GNF4877 [2041073-22-5]

TargetMol Chemicals

GNF4877 [2041073-22-5]

9

2041073-22-5

Research Use Only

GNF4877

99.40%

C25H27FN6O4

494.52

GNF4877 is a potent inhibitor of DYRK1A and GSK3beta (IC50s: 6 nM and 16 nM, respectively), resulting in the blockade of nuclear export of nuclear factor of activated T-cells (NFATc) and increased beta-cell proliferation.

3 years

CC(C)Oc1ccc(F)c(c1)-c1cnc(N)c(n1)C(=O)Nc1cnccc1N1CCC[C@H](C1)C(O)=O

-20°C

12352200