Analysis of Protein Array containing more than 19,000 full-length human proteins using Granzyme B Mouse Monoclonal Antibody (GZMB/2403). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Granzyme B Mouse Monoclonal Antibody (GZMB/2403). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.
Granzyme B antibody [GZMB/2403]
GTX18107
ApplicationsELISA, Other Application
Product group Antibodies
ReactivityHuman
TargetGZMB
Overview
- SupplierGeneTex
- Product NameGranzyme B antibody [GZMB/2403]
- Delivery Days Customer9
- Application Supplier NoteELISA: 1-5microg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsELISA, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGZMB/2403
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID3002
- Target nameGZMB
- Target descriptiongranzyme B
- Target synonymsC11; cathepsin G-like 1; CCPI; CGL1; CGL-1; CSPB; CSP-B; CTLA1; CTSGL1; cytotoxic serine protease B; cytotoxic T-lymphocyte proteinase 2; fragmentin 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); HLP; human lymphocyte protein; SECT; T-cell serine protease 1-3E
- HostMouse
- IsotypeIgG2b
- Protein IDP10144
- Protein NameGranzyme B
- Scientific DescriptionThis gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203