IHC image of CSB-PA010082LA01HU diluted at 1:800 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

GZMB Antibody

CSB-PA010082LA01HU

ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry

Product group Antibodies

TargetGZMB

Overview

Supplier
Cusabio
Product Name
GZMB Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID3002
Target name
GZMB
Target description
granzyme B
Target synonyms
C11; cathepsin G-like 1; CCPI; CGL1; CGL-1; CSPB; CSP-B; CTLA1; CTSGL1; cytotoxic serine protease B; cytotoxic T-lymphocyte proteinase 2; fragmentin 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); HLP; human lymphocyte protein; SECT; T-cell serine protease 1-3E
Host
Rabbit
Isotype
IgG
Protein IDP10144
Protein Name
Granzyme B
Scientific Description
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

GZMB Antibody

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Overview

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