Groenlandicine [38691-95-1]

TargetMol Chemicals

Groenlandicine [38691-95-1]

9

38691-95-1

Chemical

Research Use Only

Groenlandicine

99.03%

C19H16NO4

322.34

Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 microM for human recombinant aldose reductase (HRAR). Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage;Groenlandicine may be a promising anti-Alzheimers disease agent due to its potent inhibitory activity of both ChEs and beta-amyloids formation, as well as marked ONOO(-) scavenging and good ROS inhibitory capacities.

3 years

O(C)C=1C=C2C=3[N+](=CC4=C(C3)C=CC5=C4OCO5)CCC2=CC1O

-20°C

12352200