GSK-114 [1301761-96-5]

TargetMol Chemicals

GSK-114 [1301761-96-5]

4

1301761-96-5

Research Use Only

GSK-114

98.03%

C19H23N5O4S

417.48

GSK-114 is a selective inhibitor of TNNI3 interacting kinase (TNNI3K) with an IC50 of 25 nM, 40-fold significant bias for TNNI3K compared to B-Raf with an IC50 of 1000 nM, so GSK-114 has excellent Broad-spectrum kinase selectivity and sufficient oral exposure enable use in cellular and in vivo studies.

3 years

CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OC)c(OC)cc23)c1

-20°C

12352200