GSK-A1

MedChem Express

GSK-A1 [1416334-69-4]

10

1416334-69-4

Research Use Only

99.0

C29H27FN6O4S

574.63

GSK-A1 is a selective type III phosphatidylinositol 4-kinase PI4KA (PI4KIIIalpha) inhibitor with a pIC 50 of 8.5-9.8. GSK-A1 inhibits PtdIns(4,5)P2 resynthesis with an IC 50 of about 3 nM. GSK-A1 potently decreases the levels of PtdIns(4)P with a negligible effect on PtdIns(4,5)P2. GSK-A1 has the potential for anti-hepatitis C virus ( HCV ) research [1] .

O=S(C1=CC(C2=CC=C3N=C(N)N(C4=CC=C(N5CCOCC5)C=C4)C3=C2)=CN=C1OC)(NC6=CC=CC=C6F)=O

-20°C

12352200