GSK-A1 [1416334-69-4]
SYN-1219
CAS Number1416334-69-4
Product group Chemicals
Estimated Purity>95%
Molecular Weight574.6
Overview
- SupplierSYNkinase
- Product NameGSK-A1 [1416334-69-4]
- Delivery Days Customer10
- CAS Number1416334-69-4
- CertificationResearch Use Only
- Estimated Purity>95%
- Hazard InformationWarning
- Molecular FormulaC29H27FN6O4S
- Molecular Weight574.6
- Scientific DescriptionChemical. CAS: 1416334-69-4. Formula: C29H27FN6O4S. MW: 574.6. GSK-A1 is a potent PI4KA inhibitor with an IC50 of about 3nM in vitro using HEK-AT1 cells. Phosphatidylinositol 4-kinase type IIIalpha (PI4KA) is a host factor essential for hepatitis C virus replication and hence is a target for drug development. RNAi studies have shown that PI4KA is a mandatory host factor in HCV replication. Down-regulation of PI4KA appears to be reasonably tolerated by cultured cell models and results. - GSK-A1 is a potent PI4KA inhibitor with an IC50 of about 3nM in vitro using HEK-AT1 cells. Phosphatidylinositol 4-kinase type IIIalpha (PI4KA) is a host factor essential for hepatitis C virus replication and hence is a target for drug development. RNAi studies have shown that PI4KA is a mandatory host factor in HCV replication. Down-regulation of PI4KA appears to be reasonably tolerated by cultured cell models and results.
- Storage Instruction2°C to 8°C
- UNSPSC51202000