Bio-Connect

GSK-J1

M2730
AbMole BioScience
CAS Number1373422-53-7
Product group Chemicals
Estimated Purity0.9994
Molecular Weight389.45
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    GSK-J1
  • Delivery Days Customer
    9
  • CAS Number
    1373422-53-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.9994
  • Molecular Formula
    C22H23N5O2
  • Molecular Weight
    389.45
  • Scientific Description
    GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B. GSK J1 is selective for the H3K27 demethylases JMJD3 and UTX.
  • SMILES
    OC(=O)CCNC1=CC(=NC(=N1)C2=CC=CC=N2)N3CCC4=C(CC3)C=CC=C4
  • UNSPSC
    12352200