Bio-Connect

GSK1120212 (Trametinib)

M1759
AbMole BioScience
CAS Number871700-17-3
Product group Chemicals
Estimated Purity0.9981
Molecular Weight615.39
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    GSK1120212 (Trametinib)
  • Delivery Days Customer
    9
  • CAS Number
    871700-17-3
  • Category Supplier
    Chemical
  • Estimated Purity
    0.9981
  • Molecular Formula
    C26H23FIN5O4
  • Molecular Weight
    615.39
  • Scientific Description
    Trametinib (GSK1120212; Jtp-74057) is an orally effective MEK inhibitor with IC50 of 2 nM against MEK1 and MEK2, respectively. Trametinib can activate autophagy and induce apoptosis.
  • SMILES
    CN1C(=O)C(=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC4=CC=C(I)C=C4F)C5=CC(=CC=C5)NC(C)=O)C
  • UNSPSC
    12352200