GSK1120212 (Trametinib)
M1759
CAS Number871700-17-3
Product group Chemicals
Estimated Purity0.9981
Molecular Weight615.39
Overview
- SupplierAbMole BioScience
- Product NameGSK1120212 (Trametinib)
- Delivery Days Customer9
- CAS Number871700-17-3
- Category SupplierChemical
- CertificationResearch Use Only
- Estimated Purity0.9981
- Molecular FormulaC26H23FIN5O4
- Molecular Weight615.39
- Scientific DescriptionTrametinib (GSK1120212; Jtp-74057) is an orally effective MEK inhibitor with IC50 of 2 nM against MEK1 and MEK2, respectively. Trametinib can activate autophagy and induce apoptosis.
- SMILESCN1C(=O)C(=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC4=CC=C(I)C=C4F)C5=CC(=CC=C5)NC(C)=O)C
- UNSPSC12352200
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