GSK2945 [1438071-12-5]
HY-117147
CAS Number1438071-12-5
Product group Chemicals
Molecular Weight421.34
Overview
- SupplierMedChem Express
- Product NameGSK2945 [1438071-12-5]
- Delivery Days Customer10
- CAS Number1438071-12-5
- CertificationResearch Use Only
- Molecular FormulaC20H18Cl2N2O2S
- Molecular Weight421.34
- Scientific DescriptionGSK2945 is a class of tertiary amine, and is a highly specific Rev-erbalpha/REV-ERBalpha (mouse/human reverse erythroblastosis virus alpha) antagonist with EC50s of 21.5 microM and 20.8 microM, respectively. GSK2945 enhances cholesterol 7alpha-hydroxylase (CYP7A1) level and cholesterol metabolism[1].
- SMILESO=[N+](C1=CC=C(CN(CC2=CC=C(Cl)C=C2C)CC3=CC=C(Cl)C=C3)S1)[O-]
- UNSPSC12352200
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