Bio-Connect

GSK2945 [1438071-12-5]

HY-117147
MedChem Express
CAS Number1438071-12-5
Product group Chemicals
Molecular Weight421.34
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GSK2945 [1438071-12-5]
  • Delivery Days Customer
    10
  • CAS Number
    1438071-12-5
  • Certification
    Research Use Only
  • Molecular Formula
    C20H18Cl2N2O2S
  • Molecular Weight
    421.34
  • Scientific Description
    GSK2945 is a class of tertiary amine, and is a highly specific Rev-erbalpha/REV-ERBalpha (mouse/human reverse erythroblastosis virus alpha) antagonist with EC50s of 21.5 microM and 20.8 microM, respectively. GSK2945 enhances cholesterol 7alpha-hydroxylase (CYP7A1) level and cholesterol metabolism[1].
  • SMILES
    O=[N+](C1=CC=C(CN(CC2=CC=C(Cl)C=C2C)CC3=CC=C(Cl)C=C3)S1)[O-]
  • UNSPSC
    12352200