GSK5182

MedChem Express

GSK5182 [877387-37-6]

10

877387-37-6

Research Use Only

99.85

C27H31NO3

417.55

GSK5182 is a highly selective and orally active inverse agonist of estrogen-related receptor gamma (ERRgamma) with an IC 50 of 79 nM. GSK5182 does not interact with other nuclear receptors, including ERRalpha or ERalpha. GSK5182 also induces reactive oxyen species (ROS) generation in hepatocellular carcinoma (HCC) [1] [2] [3] .

OCCC/C(C1=CC=CC=C1)=C(C2=CC=C(O)C=C2)/C3=CC=C(OCCN(C)C)C=C3

-20°C,2°C to 8°C

12352200