GSK778 [2451862-42-1]

TargetMol Chemicals

GSK778 [2451862-42-1]

10

2451862-42-1

Chemical

Research Use Only

GSK778

98.42%

C30H33N5O3

511.61

GSK778 is a potent and selective inhibitor of BD1 bromodomain such as BRD2 BD1 (IC50s = 75 nM), BRD3 BD1 (IC50s = 41 nM), BRD4 BD1 (IC50s = 41 nM), and BRDT BD1 (IC50s = 143 nM). GSK778 inhibits proliferation, induces a cell cycle arrest and apoptosis.

3 years

COCc1nc2cnc3cc(-c4c(C)noc4C)c(OC[C@H]4CCNC4)cc3c2n1[C@H](C)c1ccccc1

-20°C

12352200