Western Blot analysis of Human testis tissue using GSTA3 Polyclonal Antibody at dilution of 1:250
Western Blot analysis of Human testis tissue using GSTA3 Polyclonal Antibody at dilution of 1:250
GSTA3 Polyclonal Antibody
E-AB-15087
Product group Antibodies
Overview
- SupplierElabscience
- Product NameGSTA3 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionCytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity.
- UNSPSC12352203