GW274150 [210354-22-6]

MedChem Express

GW274150 [210354-22-6]

9

210354-22-6

Research Use Only

98.0

C8H17N3O2S

219.30

GW274150 is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 microM; Kd=40 nM) and rat iNOS (ED50=1.15 microM). GW274150 also displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 exerts a protective role in an acute model of lung injury inflammation[1][2].

N[C@@H](CCSCCNC(C)=N)C(O)=O

2°C to 8°C

12352200