GW274150 [210354-22-6]

TargetMol Chemicals

GW274150 [210354-22-6]

9

210354-22-6

Chemical

Research Use Only

GW274150

0.9643

C8H17N3O2S

219.3

GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS).GW274150 has a low activity against endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) in humans and rats. GW274150 showed protective effects in an inflammatory model of acute lung injury.

3 years

C([C@@H](C(O)=O)N)CSCCNC(C)=N

-20°C

12352200