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ProductsBack/H1152 [871543-07-6]
Chemical Structure
Chemical Structure
Chemical Structure

H1152 [871543-07-6]

Research Use Only
SYN-1221
SYNkinase
CAS Number871543-07-6
Product group Chemicals
Estimated Purity>95%
Molecular Weight319.4 . 72.9
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Overview

  • Supplier
    SYNkinase
  • Product Name
    H-1152 [871543-07-6]
  • Delivery Days Customer
    10
  • CAS Number
    871543-07-6
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Warning
  • Molecular Formula
    C16H21N3O2S . 2HCl
  • Molecular Weight
    319.4 . 72.9
  • Scientific Description
    Chemical. CAS: 871543-07-6. Formula: C16H21N3O2S . 2HCl. MW: 319.4 . 72.9. H-1152 is a potent, specific, ATP-competitive and cell permeable ROCK inhibitor, with an IC50 of 12nM for ROCKII. H-1152 poorly inhibits PKA, PKC and myosin light chain kinase. Rho kinase (ROCK) activated by GTP-linked Rho phosphorylates targets that are involved in cytoskeletal remodelling, smooth muscle contraction and neuronal development. - H-1152 is a potent, specific, ATP-competitive and cell permeable ROCK inhibitor, with an IC50 of 12nM for ROCKII. H-1152 poorly inhibits PKA, PKC and myosin light chain kinase. Rho kinase (ROCK) activated by GTP-linked Rho phosphorylates targets that are involved in cytoskeletal remodelling, smooth muscle contraction and neuronal development.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200