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H-1152 dihydrochloride [871543-07-6]

H-1152 dihydrochloride [871543-07-6]

Research Use Only
T35328
TargetMol Chemicals
CAS Number871543-07-6
Product group Chemicals
Estimated Purity98.42%
Molecular Weight392.34
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    H-1152 dihydrochloride [871543-07-6]
  • Delivery Days Customer
    4
  • CAS Number
    871543-07-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    H-1152 dihydrochloride
  • Estimated Purity
    98.42%
  • Molecular Formula
    C16H23Cl2N3O2S
  • Molecular Weight
    392.34
  • Scientific Description
    H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 values of 3.03 microM, 5.68 microM, 0.360 microM, 0.745 microM and 0.180 microM, respectively.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Cl.C[C@H]1CNCCCN1S(=O)(=O)c1cccc2cncc(C)c12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200