Western blot analysis of extracts of mouse liver using HBA2 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of mouse liver using HBA2 Polyclonal Antibody at 1:1000 dilution.
HBA2 Polyclonal Antibody
E-AB-62782
Product group Antibodies
Overview
- SupplierElabscience
- Product NameHBA2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5- zeta- pseudozeta- mu- pseudoalpha-1- alpha-2- alpha-1- theta- 3. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5 untranslated regions and the introns, but they differ significantly over the 3 untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
- UNSPSC12352203