HDAC2 antibody
GTX109642
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Xenopus
TargetHDAC2
Overview
- SupplierGeneTex
- Product NameHDAC2 antibody
- Delivery Days Customer9
- Antibody SpecificityKnockdown/Knockout validation was supported by customer review data.
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.83 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID3066
- Target nameHDAC2
- Target descriptionhistone deacetylase 2
- Target synonymsHD2; histone deacetylase 2; KDAC2; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1-associated factor 1
- HostRabbit
- IsotypeIgG
- Protein IDQ92769
- Protein NameHistone deacetylase 2
- Scientific DescriptionThis gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat, Xenopus
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Anti-Excitotoxic Effects of N-Butylidenephthalide Revealed by Chemically Insulted Purkinje Progenitor Cells Derived from SCA3 iPSCs. Yang HH et al., 2022 Jan 26, Int J Mol SciRead more
- Novel Function of Avian p53 in Binding to ALV-J LTR Contributes to Its Antiviral Roles. Duan Y et al., 2022 Feb 22, mBioRead more
- Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45A. Lin HY et al., 2022 Jan, Biomed PharmacotherRead more
- Intrapulmonary administration of purified NEIL2 abrogates NF-kappaB-mediated inflammation. Tapryal N et al., 2021 Jan-Jun, J Biol ChemRead more
- The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells. Sayed IM et al., 2020 Aug 28, CellsRead more
- Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells. Chen CY et al., 2020, Front OncolRead more
- Xanthohumol Suppresses NPC1L1 Gene Expression through Downregulation of HNF-4alpha and Inhibits Cholesterol Uptake in Caco-2 Cells. Thang SK et al., 2019 Oct 9, J Agric Food ChemRead more
- A Tangeretin Derivative Inhibits the Growth of Human Prostate Cancer LNCaP Cells by Epigenetically Restoring p21 Gene Expression and Inhibiting Cancer Stem-like Cell Proliferation. Wei GJ et al., 2019 Jul 10, AAPS JRead more
- The Cholesterol-Modulating Effect of Methanol Extract of Pigeon Pea (Cajanus cajan (L.) Millsp.) Leaves on Regulating LDLR and PCSK9 Expression in HepG2 Cells. Chang HY et al., 2019 Jan 30, MoleculesRead more
- NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death. Huang D et al., 2018 Oct, Nat ImmunolRead more