HDAC2 antibody
GTX109642
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetHDAC2
Overview
- SupplierGeneTex
- Product NameHDAC2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.83 mg/ml
- ConjugateUnconjugated
- Gene ID3066
- Target nameHDAC2
- Target descriptionhistone deacetylase 2
- Target synonymsHD2; histone deacetylase 2; KDAC2; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1-associated factor 1
- HostRabbit
- IsotypeIgG
- Protein IDQ92769
- Protein NameHistone deacetylase 2
- Scientific DescriptionThis gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection.Read more
- Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntingtons disease.Read more
- Histone deacetylase 1 maintains lineage integrity through histone acetylome refinement during early embryogenesis.Read more
- Anti-Excitotoxic Effects of N-Butylidenephthalide Revealed by Chemically Insulted Purkinje Progenitor Cells Derived from SCA3 iPSCs. Yang HH et al., 2022 Jan 26, Int J Mol SciRead more
- Novel Function of Avian p53 in Binding to ALV-J LTR Contributes to Its Antiviral Roles. Duan Y et al., 2022 Feb 22, mBioRead more
- Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45A. Lin HY et al., 2022 Jan, Biomed PharmacotherRead more
- Intrapulmonary administration of purified NEIL2 abrogates NF-kappaB-mediated inflammation. Tapryal N et al., 2021 Jan-Jun, J Biol ChemRead more
- The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells. Sayed IM et al., 2020 Aug 28, CellsRead more
- Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells. Chen CY et al., 2020, Front OncolRead more
- Xanthohumol Suppresses NPC1L1 Gene Expression through Downregulation of HNF-4alpha and Inhibits Cholesterol Uptake in Caco-2 Cells. Thang SK et al., 2019 Oct 9, J Agric Food ChemRead more
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