More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/HDAC2 antibody

HDAC2 antibody

GTX109642
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat, Xenopus
TargetHDAC2
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    HDAC2 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Knockdown/Knockout validation was supported by customer review data.
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.83 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3066
  • Target name
    HDAC2
  • Target description
    histone deacetylase 2
  • Target synonyms
    HD2; histone deacetylase 2; KDAC2; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1-associated factor 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92769
  • Protein Name
    Histone deacetylase 2
  • Scientific Description
    This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat, Xenopus
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection.
    Read more
  • Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntingtons disease.
    Read more
  • Histone deacetylase 1 maintains lineage integrity through histone acetylome refinement during early embryogenesis.
    Read more
  • Anti-Excitotoxic Effects of N-Butylidenephthalide Revealed by Chemically Insulted Purkinje Progenitor Cells Derived from SCA3 iPSCs. Yang HH et al., 2022 Jan 26, Int J Mol Sci
    Read more
  • Novel Function of Avian p53 in Binding to ALV-J LTR Contributes to Its Antiviral Roles. Duan Y et al., 2022 Feb 22, mBio
    Read more
  • Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45A. Lin HY et al., 2022 Jan, Biomed Pharmacother
    Read more
  • Intrapulmonary administration of purified NEIL2 abrogates NF-kappaB-mediated inflammation. Tapryal N et al., 2021 Jan-Jun, J Biol Chem
    Read more
  • The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells. Sayed IM et al., 2020 Aug 28, Cells
    Read more
  • Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells. Chen CY et al., 2020, Front Oncol
    Read more
  • Xanthohumol Suppresses NPC1L1 Gene Expression through Downregulation of HNF-4alpha and Inhibits Cholesterol Uptake in Caco-2 Cells. Thang SK et al., 2019 Oct 9, J Agric Food Chem
    Read more