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HDAC2 antibody

GTX109642
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetHDAC2
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Overview

  • Supplier
    GeneTex
  • Product Name
    HDAC2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.83 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3066
  • Target name
    HDAC2
  • Target description
    histone deacetylase 2
  • Target synonyms
    HD2, KDAC2, RPD3, YAF1, histone deacetylase 2, YY1-associated factor 1, protein deacylase HDAC2, transcriptional regulator homolog RPD3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92769
  • Protein Name
    Histone deacetylase 2
  • Scientific Description
    This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection.
    Read this paper
  • Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntingtons disease.
    Read this paper
  • Histone deacetylase 1 maintains lineage integrity through histone acetylome refinement during early embryogenesis.
    Read this paper
  • Anti-Excitotoxic Effects of N-Butylidenephthalide Revealed by Chemically Insulted Purkinje Progenitor Cells Derived from SCA3 iPSCs. Yang HH et al., 2022 Jan 26, Int J Mol Sci
    Read this paper
  • Novel Function of Avian p53 in Binding to ALV-J LTR Contributes to Its Antiviral Roles. Duan Y et al., 2022 Feb 22, mBio
    Read this paper
  • Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45A. Lin HY et al., 2022 Jan, Biomed Pharmacother
    Read this paper
  • Intrapulmonary administration of purified NEIL2 abrogates NF-kappaB-mediated inflammation. Tapryal N et al., 2021 Jan-Jun, J Biol Chem
    Read this paper
  • The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells. Sayed IM et al., 2020 Aug 28, Cells
    Read this paper
  • Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells. Chen CY et al., 2020, Front Oncol
    Read this paper
  • Xanthohumol Suppresses NPC1L1 Gene Expression through Downregulation of HNF-4alpha and Inhibits Cholesterol Uptake in Caco-2 Cells. Thang SK et al., 2019 Oct 9, J Agric Food Chem
    Read this paper