HDAC3 antibody [HL1749]

GeneTex

HDAC3 antibody [HL1749]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

HL1749

1 mg/ml

Unconjugated

HDAC3

histone deacetylase 3

HD3; histone deacetylase 3; KDAC3; RPD3; RPD3-2; SMAP45

Rabbit

IgG

Histone deacetylase 3

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]

Drosophila, Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203