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Heavy chain cardiac Myosin antibody [3-48]

Research Use Only
GTX20015
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityBovine, Canine, Human, Mouse, Porcine, Rabbit, Rat
TargetMYH6
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Overview

  • Supplier
    GeneTex
  • Product Name
    Heavy chain cardiac Myosin antibody [3-48]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody is myosin alpha and beta heavy chain specific. Affinity constants for:Human ventricular myosin heavy chains - 3.33 x 10<sup>8</sup>M<sup>-1</sup>Human atrial myosin heavy chains - 1.48 x 10<sup>8</sup>M<sup>-1</sup> Human skeletal muscle myo
  • Application Supplier Note
    For ELISA: Use at an assay dependant dilution. For IF: Use at an assay dependant dilution. For IHC-Fr: Use at an assay dependant dilution. For WB: Use at an assay dependant dilution. Predicted molecular weight: 223 kDa. Optimal dilutions/concentrations should be determined by the researcher.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    3-48
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID4624
  • Target name
    MYH6
  • Target description
    myosin heavy chain 6
  • Target synonyms
    alpha-MHC; ASD3; CMD1EE; CMH14; MYHC; MYHCA; myHC-alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); myosin-6; SSS3
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    3-48 antibody cross-reacts with heavy chains of human myosin isolated from: slow skeletal muscle, fast skeletal muscle, eye muscle, and streptococcal M5 peptide. It does not react with human platelet, smooth muscle myosin heavy chains, myosin light chains, myosin fragments circulating in blood of patients with myocardial infarction, nor does it react with any other human tissue antigens or blood cells.
  • Reactivity
    Bovine, Canine, Human, Mouse, Porcine, Rabbit, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CircCLTH promotes skeletal muscle development and regeneration. Chen M et al., 2022 Dec, Epigenetics
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  • The circular RNA circCPE regulates myoblast development by sponging miR-138. Ru W et al., 2021 Sep 8, J Anim Sci Biotechnol
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  • Beta-agonist drugs modulate the proliferation and differentiation of skeletal muscle cells in vitro. Flavie Ouali BE et al., 2021 Jul, Biochem Biophys Rep
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  • CircINSR Regulates Fetal Bovine Muscle and Fat Development. Shen X et al., 2020, Front Cell Dev Biol
    Read more
  • Circular RNA circMYL1 Inhibit Proliferation and Promote Differentiation of Myoblasts by Sponging miR-2400. Elnour IE et al., 2021 Jan 16, Cells
    Read more
  • Familial Recurrent Myocarditis Triggered by Exercise in Patients With a Truncating Variant of the Desmoplakin Gene. Poller W et al., 2020 May 18, J Am Heart Assoc
    Read more
  • Bta-miR-885 promotes proliferation and inhibits differentiation of myoblasts by targeting MyoD1. Elsaeid Elnour I et al., 2020 Oct, J Cell Physiol
    Read more
  • Circular RNA TTN Acts As a miR-432 Sponge to Facilitate Proliferation and Differentiation of Myoblasts via the IGF2/PI3K/AKT Signaling Pathway. Wang X et al., 2019 Dec 6, Mol Ther Nucleic Acids
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  • Bioelectronic Recordings of Cardiomyocytes with Accumulation Mode Electrolyte Gated Organic Field Effect Transistors. Kyndiah A et al., 2020 Feb 15, Biosens Bioelectron
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  • Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts. Garreta E et al., 2016 Aug, Biomaterials
    Read more