HEF1 antibody [14A11]

GeneTex

HEF1 antibody [14A11]

9

Specific for human HEF1 localized in mitotic cells in the spindle and the centrosome. It does not recognize p130Cas. Have not tested it on Sin1

Recommended Starting Dilutions:at 1microg of antibody per 200microg of whole cell lysate for IP, & 1:100 for IFOptimal dilutions should be determined experimentally by the researcher.

ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry

Research Use Only

Monoclonal

14A11

Unconjugated

Liquid

NEDD9

neural precursor cell expressed, developmentally down-regulated 9

Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate related protein Cas-L; enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; neural precursor cell expressed developmentally down-regulated protein 9; p130Cas-related protein; renal carcinoma antigen NY-REN-12

Mouse

IgG2b

Enhancer of filamentation 1

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Human

-20°C or -80°C,2°C to 8°C

12352203