HEF1 antibody [2G9]

GeneTex

HEF1 antibody [2G9]

9

Human, mouse, rat HEF-1. Does not recognize p130Cas. Have not tested on Sin1. This mAb mostly detects HEF1 localized at the focal adhesion sites

Recommended Starting Dilutions:For WB: Use at 1:2000-1:6000For IP: Use at 1:1000For ICC/IF: Use at 1:500 Optimal dilutions should be determined experimentally by the researcher.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

Research Use Only

Monoclonal

2G9

Unconjugated

NEDD9

neural precursor cell expressed, developmentally down-regulated 9

Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate related protein Cas-L; enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; neural precursor cell expressed developmentally down-regulated protein 9; p130Cas-related protein; renal carcinoma antigen NY-REN-12

Mouse

IgG1

Enhancer of filamentation 1

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203