Heliquinomycin [178182-49-5]

TargetMol Chemicals

Heliquinomycin [178182-49-5]

16

178182-49-5

Chemical

Research Use Only

Heliquinomycin

C33H30O17

698.586

Heliquinomycin is a bacterial metabolite originally isolated fromStreptomycesthat has diverse biological activities.1It is active against a variety of Gram-positive bacteria, including strains ofB. anthracis, B. subtilis, and methicillin-sensitive or -resistantS. aureus(MICs = <0.05-0.39 microg/ml). Heliquinomycin inhibits the activity of DNA helicase with a Kivalue of 6.8 microM. It reduces the growth of L1210 leukemia, B16 melanoma, and FS-3 fibrosarcoma cells (IC50s = 0.97, 0.89, and 0.83 microg/ml, respectively).

3 years

CO[C@@H]1C[C@H](O[C@@H]2c3c(O[C@@]22Oc4c(C[C@H]2O)cc2cc(oc(=O)c2c4O)C(=O)OC)c(O)c2C(=O)C(OC)=CC(=O)c2c3O)O[C@@H](C)[C@@H]1O - c:42 -

-20°C

12352200