Heliquinomycin [178182-49-5]

AdipoGen Life Sciences

Heliquinomycin

10

178182-49-5

Research Use Only

>80%

Warning

C33H30O17

698.6

Antibiotic [1]. DNA helicase inhibitor [1]. Inhibits the DNA helicase activity of the human minichromosome maintenance (MCM) 4/6/7 complex [3, 4]. Topoisomerase I and II inhibitor (weaker than DNA helicase) [2]. DNA and RNA synthesis inhibitor in cell culture. Does not inhibit protein synthesis [2]. Induces cell cycle arrest [2]. Anticancer compound [1, 2]. Antibacterial against Gram-positive bacteria [1]. - Chemical. CAS: 178182-49-5. Formula: C33H30O17. MW: 698.6. Isolated from Streptomyces sp. MJ929-SF2. Antibiotic. DNA helicase inhibitor. Inhibits the DNA helicase activity of the human minichromosome maintenance (MCM) 4/6/7 complex. Topoisomerase I and II inhibitor (weaker than DNA helicase). DNA and RNA synthesis inhibitor in cell culture. Does not inhibit protein synthesis. Induces cell cycle arrest. Anticancer compound. Antibacterial against Gram-positive bacteria.

COC1CC(O[C@@H]2C3=C(O[C@@]22OC4=C(C[C@H]2O)C=C2C=C(OC(=O)C2=C4O)C(=O)OC)C(O)=C2C(=O)C(OC)=CC(=O)C2=C3O)OC(C)C1O

-20°C,2°C to 8°C

12352200