The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA447962(HIF1AN Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA447962(HIF1AN Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
HIF1AN Antibody
CSB-PA447962
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetHIF1AN
Overview
- SupplierCusabio
- Product NameHIF1AN Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55662
- Target nameHIF1AN
- Target descriptionhypoxia inducible factor 1 subunit alpha inhibitor
- Target synonymsFIH1, hypoxia-inducible factor 1-alpha inhibitor, FIH-1, factor inhibiting HIF-1, factor inhibiting HIF1, hypoxia inducible factor 1 alpha subunit inhibitor, hypoxia-inducible factor asparagine hydroxylase, peptide-aspartate beta-dioxygenase
- HostRabbit
- IsotypeIgG
- Protein IDQ9NWT6
- Protein NameHypoxia-inducible factor 1-alpha inhibitor
- Scientific DescriptionHypoxia-inducible factor 1-alpha inhibitor is a protein that in humans is encoded by the HIF1AN gene. Hydroxylates HIF-1 alpha at Asp-803 in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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