HIF1AN antibody

GeneTex

HIF1AN antibody

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

HIF1AN

hypoxia inducible factor 1 subunit alpha inhibitor

FIH1, hypoxia-inducible factor 1-alpha inhibitor, FIH-1, factor inhibiting HIF-1, factor inhibiting HIF1, hypoxia inducible factor 1 alpha subunit inhibitor, hypoxia-inducible factor asparagine hydroxylase, peptide-aspartate beta-dioxygenase

Rabbit

IgG

Hypoxia-inducible factor 1-alpha inhibitor

Hydroxylates HIF-1 alpha at Asp-803 in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.

-20°C or -80°C,2°C to 8°C

12352203