HIF2 alpha antibody [GT125]
GTX632015
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetEPAS1
Overview
- SupplierGeneTex
- Product NameHIF2 alpha antibody [GT125]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:700. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT125
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2034
- Target nameEPAS1
- Target descriptionendothelial PAS domain protein 1
- Target synonymsbasic-helix-loop-helix-PAS protein MOP2; bHLHe73; class E basic helix-loop-helix protein 73; ECYT4; endothelial PAS domain-containing protein 1; EPAS-1; HIF-1-alpha-like factor; HIF-1alpha-like factor; HIF2A; HIF-2-alpha; HIF2-alpha; HLF; hypoxia-inducible factor 2 alpha; member of PAS protein 2; MOP2; PAS domain-containing protein 2; PASD2
- HostMouse
- IsotypeIgG1
- Protein IDQ99814
- Protein NameEndothelial PAS domain-containing protein 1
- Scientific DescriptionThis gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- PRDM16 suppresses HIF-targeted gene expression in kidney cancer. Kundu A et al., 2020 Jun 1, J Exp MedRead more
- Physapubescin selectively induces apoptosis in VHL-null renal cell carcinoma cells through down-regulation of HIF-2alpha and inhibits tumor growth. Chen L et al., 2016 Sep 1, Sci RepRead more
- Role of Mitochondrial DNA Copy Number Alteration in Human Renal Cell Carcinoma. Lin CS et al., 2016 May 25, Int J Mol SciRead more