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ProductsBack/HIF2 alpha antibody [ep190b]
WB analysis of hypoxia-treated A549 cell lysate using GTX30123 HIF2 alpha antibody [ep190b]. Lane 1: normoxic A549 lysate control Lane 2: hypoxic A549 lysate
WB analysis of hypoxia-treated A549 cell lysate using GTX30123 HIF2 alpha antibody [ep190b]. Lane 1: normoxic A549 lysate control Lane 2: hypoxic A549 lysate
WB analysis of hypoxia-treated A549 cell lysate using GTX30123 HIF2 alpha antibody [ep190b]. Lane 1: normoxic A549 lysate control Lane 2: hypoxic A549 lysate

HIF2 alpha antibody [ep190b]

GTX30123
GeneTex
ApplicationsGel Shift Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHamster, Human, Mouse, Rat
TargetEPAS1
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Overview

  • Supplier
    GeneTex
  • Product Name
    HIF2 alpha antibody [ep190b]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1 - 2 microg/ml. IHC-P: 1:150 - 1:300. FCM: 1:400. ELISA: 1:100 - 1:2000. IHC: 1:150 - 1:300. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Gel Shift Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ep190b
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2034
  • Target name
    EPAS1
  • Target description
    endothelial PAS domain protein 1
  • Target synonyms
    ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73, endothelial PAS domain-containing protein 1, EPAS-1, HIF-1-alpha-like factor, HIF-1alpha-like factor, HIF-2-alpha, HIF2-alpha, PAS domain-containing protein 2, basic-helix-loop-helix-PAS protein MOP2, class E basic helix-loop-helix protein 73, hypoxia-inducible factor 2 alpha, member of PAS protein 2
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ99814
  • Protein Name
    Endothelial PAS domain-containing protein 1
  • Scientific Description
    This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq]
  • Reactivity
    Hamster, Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    41116161

References

  • Changes in cell fate determine the regenerative and functional capacity of the developing kidney before and after release of obstruction. Nagalakshmi VK et al., 2018 Dec 12, Clin Sci (Lond)
    Read this paper
  • Thiamine deficiency activates hypoxia inducible factor-1alpha to facilitate pro-apoptotic responses in mouse primary astrocytes. Zera K et al., 2017, PLoS One
    Read this paper
  • VHL and PTEN loss coordinate to promote mouse liver vascular lesions. Chen S et al., 2010 Mar, Angiogenesis
    Read this paper
  • Identification of Ror2 as a hypoxia-inducible factor target in von Hippel-Lindau-associated renal cell carcinoma. Wright TM et al., 2010 Apr 23, J Biol Chem
    Read this paper
  • ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress. Myers K et al., 2009 Jan, PLoS Genet
    Read this paper
  • VHL type 2B mutations retain VBC complex form and function. Hacker KE et al., 2008, PLoS One
    Read this paper
  • Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I. Catrina SB et al., 2006 Aug 1, Clin Cancer Res
    Read this paper

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